Gene Transcription Regulation Database

The most complete collection of uniformly processed ChIP-seq data to identify transcription factor binding sites for human and mouse. Convenient web interface with advanced search, browsing and genome browser based on the BioUML platform. For support or any questions contact ivan@nulldote.ru

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How was it constructed?

ChIP-seq experiment information and raw data were collected from publically available sources. Sequenced reads were aligned using Bowtie2 and ChIP-seq peaks were called using 4 different methods. Peaks were merged into clusters and metaclusters to produce non-redundant set of transcription factor binding sites.

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version 18.01

  • 3340 new 12168 ChIP-seq experiments
  • 53 new 766 Transcription factors
  • 27% new 508 023 543 763 ChIP-seq reads
  • 29% new 335 707 127 761 Reads aligned
  • 31% new 961 923 622 ChIP-seq peaks
  • 20% new 527 498 674 Clusters
  • 14% new 70 338 813 Metaclusters
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How to cite

GTRD: a database of transcription factor binding sites identified by ChIP-seq experiments. I.S. Yevshin, R.N. Sharipov, T.F. Valeev, A.E. Kel, F.A. Kolpakov. Nucleic Acids Res. 2017 Jan 4;45(D1):D61-D67.


Users may freely use the GTRD database for non-commercial purposes as long as they properly cite it. If you intend to use GTRD for a commercial purpose, please contact ivan@nulldote.ru to arrange a license.

Studies citing GTRD

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